N-Acetyl cysteine for prevention of contrast induced nephropathy

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Title N-Acetyl cysteine for prevention of contrast induced nephropathy
 
Creator Anisul Awal; Department of Cardiology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbag, Dhaka
Syed Ali Hasan; Department of Cardiology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbag, Dhaka
Md Abu Siddique; Department of Cardiology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbag, Dhaka
Bikash Subedi; Department of Cardiology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbag, Dhaka
Jahanara Arzu; Department of Cardiology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbag, Dhaka
Quazi Arif Ahmed; Department of Cardiology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbag, Dhaka
KMHS Sirajul Haque; Department of Cardiology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbag, Dhaka
Md Ashraf Uddin Sultan; Department of Cardiology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbag, Dhaka
Neena Islam; Department of Cardiology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbag, Dhaka
 
Subject Cardiology
Anti Oxidant; contrast induced nephropathy
 
Description The antioxidant N-acetyl Cysteine prevents contrast induced nephropathy in patients with impaired renal function who undergo coronary angiogeaphy. However its role in Bangladeshi population is not clear. This study was done determine whether oral acetylcysteine prevents contrast induced nephropathy in high risk patients.100 patients with mild to moderate renal insufficiency who are undergoing elective coronary angiography with or without intervention.50 patients were randomy assigned to receive oral N acetyl cysteine (600mg) twice daily on the day before and on the day of procedure. All patients received low osmolar contrast agent.10 (20%) control patients (no premedicationgroup) and none of acetyl cysteine (0%) group developed a more than 25% increase in serum creatinine level within 48 hours after contrast exposure. Acetyl cysteine prevents contrast induced nephropathy. Keywords : Anti Oxidant; contrast induced nephropathy. DOI: 10.3329/uhj.v5i2.4554 University Heart Journal Vol.5(2) July 2009 pp.56-58
 
Publisher Academic and Research Cell , Department of Cardiology, University Cardiac Centre, BSMMU
 
Contributor
 
Date 2010-03-09
 
Type
 
Format application/pdf
 
Identifier http://www.banglajol.info/index.php/UHJ/article/view/4554
 
Source University Heart Journal; Vol 5, No 2 (2009); 56-58
 
Language en
 
Coverage Bangladesh