A Study on the Synthesis of 5, 7-Diaryl-1,2,3,4-tetrahydro-2, 4-dioxo-5H-pyrano [2,3-d]pyrimidines
Bangladesh Journals Online
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| Title |
A Study on the Synthesis of 5, 7-Diaryl-1,2,3,4-tetrahydro-2, 4-dioxo-5H-pyrano [2,3-d]pyrimidines
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| Creator |
MG Ahmed; Department of Chemistry, University of Dhaka, Dhaka-1000
UKR Romman; Department of Chemistry, University of Dhaka, Dhaka-1000 SM Ahmed; bFaculty of Science, American International University-Bangladesh (AIUB), Banani, Dhaka-1213, Bangladesh Khondaker Akhter; Department of Chemistry, University of Dhaka, Dhaka-1000 ME Halim; Department of Chemistry, University of Dhaka, Dhaka-1000 M Salauddin; Department of Chemistry, University of Dhaka, Dhaka-1000 |
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| Subject |
Applied Science
pyrimidines |
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| Description |
5,7-Diphenyl-1,2,3,4-tetrahydro-2,4-dioxo-5H-pyrano[2,3-d]pyrimidine (4a) has been synthesized in single-step by the condensation of barbituric acid (1) with benzylideneacetophenone (2a) in glacial acetic acid in the presence of phosphorous pentoxide. Reaction of barbituric acid (1) with arylideneacetophenones (2b-d) which gave the corresponding adducts of 5-(1,3-diaryl-1-oxopropyl) pyrimidine (1H, 3H, 5H)-2,4,6-triones (3a-c) previously in 50 % aqueous ethanol which on further reflux in gl. acetic acid in the presence of phosphorous pentoxide also gave the corresponding pyranopyrimidines 5,7-diaryl-1,2,3,4-tetrahydro-2,4-dioxo-5H-pyrano [2,3- d]pyrimidines (4b-d). The structures of the compounds 4a-d were characterized by their UV, IR, 1H NMR and 13C NMR spectral data.
Bangladesh J. Sci. Ind. Res. 41(3-4), 119-128, 2006
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| Publisher |
Bangladesh Council of Scientific & Industrial Research
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| Date |
2007-08-01
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| Type |
—
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| Format |
application/pdf
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| Identifier |
http://www.banglajol.info/index.php/BJSIR/article/view/281
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| Source |
Bangladesh Journal of Scientific and Industrial Research; Vol 41, No 3 (2006); 119-128
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| Language |
en
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| Coverage |
Bangladesh
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