A Benzofuranone from the Flowers of Nyctanthes arbortristis and its Antibacterial and Cytotoxic Activities
Bangladesh Journals Online
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A Benzofuranone from the Flowers of Nyctanthes arbortristis and its Antibacterial and Cytotoxic Activities
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| Creator |
Naznin Ara Khatune; Department of Pharmacy, University of Rajshahi, Rajshahi 6205
M Asik Mossadik; Department of Pharmacy, University of Rajshahi, Rajshahi 6205 M Mukhlesur Rahman; Department of Pharmacy, University of Rajshahi, Rajshahi 6205 Proma Khondkar; Department of Pharmacy, University of Rajshahi, Rajshahi 6205 M Ekramul Haque; mukhlesurrah@yahoo.co.uk Alexander I Gray; Department of Pharmaceutical Sciences, University of Strathclyde, SIBS Building, 27 Taylor Street, Glasgow G4 ONR, Scotland, UK |
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| Subject |
Pharmacy
Nyctanthes arbortristis; Nyctantheceae; 3,3a,7,7a-tetrahydro-3a-hydroxy-6(2H)-benzofuranone; Antibacterial; Cytotoxicity |
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| Description |
A benzofuranone, 3,3a,7,7a-tetrahydro-3a-hydroxy-6(2H)-benzofuranone (1), was isolated from the flower of Nyctanthes arbortristis Linn. The compound was identified by 1D and 2D NMR and MS analyses. It showed significant antibacterial activity against both Gram positive and Gram negative bacteria. The LC50 of the compound was found to be 8.73 mg/ml in brine shrimp lethality bioassay.
Key words: Nyctanthes arbortristis, Nyctantheceae; 3,3a,7,7a-tetrahydro-3a-hydroxy-6(2H)-benzofuranone, Antibacterial, Cytotoxicity
Dhaka Univ. J. Pharm. Sci. Vol.4(1) 2005
The full text is of this article is available at the Dhaka Univ. J. Pharm. Sci. website
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| Publisher |
Dhaka University
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| Date |
2007-06-15
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—
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| Identifier |
http://www.banglajol.info/index.php/JPharma/article/view/191
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| Source |
Dhaka University Journal of Pharmaceutical Sciences; Vol 4, No 1 (2005)
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| Language |
en
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