Effect of Manganese on the Activity of Antibiotic Against Microorganisms
Bangladesh Journals Online
View Archive Info| Field | Value | |
| Title |
Effect of Manganese on the Activity of Antibiotic Against Microorganisms
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| Creator |
S Rahman; Faculty of Pharmacy, University of Dhaka, Dhaka 1000
Pinky Karim; Department of Pharmacy, The University of Asia Pacific, Dhanmondi, Dhaka Abu Asad Chowdhury; Faculty of Pharmacy, University of Dhaka, Dhaka 1000 Abul Hasnat; Faculty of Pharmacy, University of Dhaka, Dhaka 1000 |
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| Subject |
Pharmacy
Antibiotics; Manganese; Antibacterial activity |
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| Description |
Manganese is an important element in biological system. It is essential for enzymatic activity, maintaining three-dimensional structure of protein, for the synthesis of nucleic acid and protein etc. Deficiency of manganese causes different life threatening diseases. Because of this, the optimum level of manganese must be maintained in all biological system. This experiment, therefore, was designed to evaluate the effect of manganese on the activity of different antibiotics (ciprofloxacin, cephradine, amoxicillin, gentamycin, tetracycline, cloxacillin, nalidixic acid, ceftriaxone, metronidazole and carbenicillin) against different microorganisms. It has been observed that antimicrobial activity of an antibiotic increased significantly with concomitant use of manganese salt ranging from 600-6000 ng per antibiotic disc (P < 0.05). It is revealed from the experiment that manganese increases the activity of antibiotic against bacterial strains.
Key words: Antibiotics, Manganese, Antibacterial activity.
Dhaka Univ. J. Pharm. Sci. Vol.4(1) 2005
The full text is of this article is available at the Dhaka Univ. J. Pharm. Sci. website
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| Publisher |
Dhaka University
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| Date |
2007-06-15
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| Type |
—
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| Identifier |
http://www.banglajol.info/index.php/JPharma/article/view/194
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| Source |
Dhaka University Journal of Pharmaceutical Sciences; Vol 4, No 1 (2005)
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| Language |
en
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