Developement of Quantitative Analysis of Sparfloxacin by High Performance Liquid Chromatography
Bangladesh Journals Online
View Archive Info| Field | Value | |
| Title |
Developement of Quantitative Analysis of Sparfloxacin by High Performance Liquid Chromatography
|
|
| Creator |
Narun Nahar Rahman; Department of Pharmaceutical Chemistry, University of Dhaka, Dhaka-1000
Shahabuddin Ahmad; Department of Pharmaceutical Chemistry, University of Dhaka, Dhaka-1000 |
|
| Subject |
Pharmacy
Sparfloxacin; HPLC; analysis |
|
| Description |
An attempt has been made to develop a simple, sensitive and rapid high performance liquid chromatographic (HPLC) method of analysis for sparfloxacin using 35% acetonitrile in buffer solution as mobile phase. Buffer solution (40 mM of sodium dihydrogen phosphate in de-ionized water) was used as solvent to dissolve sparfloxacin and 0.05mg/ml stock solution was prepared. Sparfloxacin solution was scanned with UV-spectrophotometer and the absorption maximum (λmax) was found at 292 rim. This method was successfully applied to four tablet dosage forms of sparfloxacin encoded as ?, ?, ?, and ?, from four different companies and the result was found to be satisfactory and reproducible.
Key words: Sparfloxacin, HPLC, analysis
Dhaka Univ. J. Pharm. Sci. 6(1): 21-23, 2007 (June)
The full text is of this article is available at the Dhaka Univ. J. Pharm. Sci. website
|
|
| Publisher |
Dhaka University
|
|
| Date |
2007-08-09
|
|
| Type |
—
|
|
| Format |
application/pdf
|
|
| Identifier |
http://www.banglajol.info/index.php/JPharma/article/view/339
|
|
| Source |
Dhaka University Journal of Pharmaceutical Sciences; Vol 6, No 1 (2007); 21-23
|
|
| Language |
en
|
|
| Coverage |
Bangladesh
|
|