Immunoglobulin (IgG, IgA and IgM) Profiles in Schizophrenic Patients
Bangladesh Journals Online
View Archive Info| Field | Value | |
| Title |
Immunoglobulin (IgG, IgA and IgM) Profiles in Schizophrenic Patients
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| Creator |
Pinky Karim; Department of Pharmacy, University of Asia Pacific, Dhanmondi, Dhaka
AFM Nazmus Sadat; Department of Pharmacy, University of Asia Pacific, Dhanmondi, Dhaka Md Iqbal Hossain; Department of Clinical Pharmacy and Pharmacology, Faculty of Pharmacy, University of Dhaka, Dhaka-1000 MMA Shalahuddin Qusar; Department of Psychiatry, Bangabandu Sheikh Mujib Medical University, Dhaka SK Nazrul Islam; Institute of Nutrition and Food Sciences, University of Dhaka, Dhaka-1000 Abul Hasnat; Department of Clinical Pharmacy and Pharmacology, Faculty of Pharmacy, University of Dhaka, Dhaka-1000 |
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| Subject |
Pharmacy
Immunoglobulin; Schizophrenia; Psychiatry |
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| Description |
The aim of this study was to determine the serum immunoglobulin concentration in both schizophrenic patients and healthy individuals. The study was conducted with 30 (thirty) schizophrenic patients (24 males and 6 females, aged 55.4±13.0 years); age and gender-matched, control subjects were enrolled. An enzyme-linked immunosorbent assay (ELISA) was employed to analyze the serum immunoglobulin concentrations. Results showed that the concentrations of serum IgG, IgM and IgA were not changed significantly than that of the cohort controls. The IgG level was found to be 15.23 ± 3.82 g/l (p = 0.341) in the schizophrenic patients, while it was 14.36 ± 3.37 g/l in the cohort controls. IgM and IgA concentrations were 6.19 ± 2.36 g/l (p = 0.861) and 4.85 ± 1.70 g/l (p = 0.362) in the schizophrenic patients, whereas those were 6.00 ± 2.05 g/l and 4.48 ± 1.39 g/l, respectively, in healthy volunteers. In many psychiatric disorders, immunoglobulin levels changed significantly and have been used as a tool for the preliminary diagnosis of those diseases. The study concludes that serum immunoglobulin levels in schizophrenic patients may not be useful as a diagnostic tool for the identification of this disorder.
Key words: Immunoglobulin, Schizophrenia, Psychiatry
Dhaka Univ. J. Pharm. Sci. Vol.4(1) 2005
The full text is of this article is available at the Dhaka Univ. J. Pharm. Sci. website
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| Publisher |
Dhaka University
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| Date |
2007-06-15
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| Type |
—
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| Identifier |
http://www.banglajol.info/index.php/JPharma/article/view/197
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| Source |
Dhaka University Journal of Pharmaceutical Sciences; Vol 4, No 1 (2005)
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| Language |
en
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