Phytochemical and Biological Investigations of Phyllanthus reticulatus

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Title Phytochemical and Biological Investigations of Phyllanthus reticulatus
 
Creator Taslima Begum; Phytochemical Research Laboratory, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka-1000
Mohammad S Rahman; Phytochemical Research Laboratory, Department of Pharmaceutical Chemistry, University of Dhaka, Dhaka-1000
Mohammad A Rashid; Centre for Biomedical Research, University of Dhaka, Dhaka-1000
 
Subject Pharmacy
Phyllanthus reticulates; Euphorbiaceae; Scopoletin; Brine shrimp lethality bioassay; Antimicrobial
 
Description Scopoletin (1) was isolated from the chloroform soluble fraction of a methanol extract of the stem bark of Phyllanthus reticulates (Family: Euphorbiaceae). The petroleum ether, carbon tetrachloride and choloroform soluble fractions of this methanol extract were subjected to antimicrobial screening and brine shrimp lethality bioassay. All of the partitionates showed moderate to strong inhibitory activity to microbial growth while the chloroform soluble fraction showed strongest cytotoxicity having LC50 1.99 ?g/ml. Key words: Phyllanthus reticulates, Euphorbiaceae, Scopoletin, Brine shrimp lethality bioassay, Antimicrobial Dhaka Univ. J. Pharm. Sci. Vol.5(1-2) 2006 The full text is of this article is available at the Dhaka Univ. J. Pharm. Sci. website
 
Publisher Dhaka University
 
Date 2007-06-20
 
Type
 
Format application/pdf
 
Identifier http://www.banglajol.info/index.php/JPharma/article/view/223
 
Source Dhaka University Journal of Pharmaceutical Sciences; Vol 5, No 1 (2006); 21-23
 
Language en