Biological Screening of Zizyphus rugosa and Zizyphus oenoplia extractives

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Title Biological Screening of Zizyphus rugosa and Zizyphus oenoplia extractives
 
Creator M Shoeb; Department of Chemistry, University of Dhaka, Dhaka-1000
MIR Mamun; Department of Chemistry, University of Dhaka, Dhaka-1000
N Nahar; Department of Chemistry, University of Dhaka, Dhaka-1000
M Mosihuzzaman; Department of Chemistry, University of Dhaka, Dhaka-1000
 
Subject Pharmacy
Zizyphus rugosa; Zizyphus oenoplia; Antibacterial; Antifungal; b-glucuronidase inhibition
 
Description Different extracts of the leaves and barks of Zizyphus rugosa and Zizyphus oenoplia were studied for their antibacterial, antifungal, and b-glucuronidase inhibitory activities. The methanol extract of Z. rugosa bark showed significant antibacterial activity against Streptococcus pyogens, Staphylococcus aureus and Pseudomonas aerogenes whereas the methanol extract of leaves demonstrated moderate activity against Salmonella typhi. The chloroform and methanol extracts of Z. oenoplia showed good activity against a few bacteria strains. The chloroform extracts of the barks and leaves of Z. rugosaalso showed antifungal activity. The methanol and ethyl acetate extracts of the bark of Z. rugosa revealed significant b-glucuronidase inhibitory activity. Lupeol, betuline, betulinaldehyde and betulinic acid, isolated from Z. rugosa, also showed good activity against a few bacteria. Key words: Zizyphus rugosa, Zizyphus oenoplia, Antibacterial, Antifungal, b-glucuronidase inhibition Dhaka Univ. J. Pharm. Sci. Vol.4(2) 2005 The full text is of this article is available at the Dhaka Univ. J. Pharm. Sci. website
 
Publisher Dhaka University
 
Date 2007-06-18
 
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Identifier http://www.banglajol.info/index.php/JPharma/article/view/216
 
Source Dhaka University Journal of Pharmaceutical Sciences; Vol 4, No 2 (2005)
 
Language en