Methylkarranjic acid and Pongamol from Derris indica Seeds and their Antibacterial Activity
Bangladesh Journals Online
View Archive Info| Field | Value | |
| Title |
Methylkarranjic acid and Pongamol from Derris indica Seeds and their Antibacterial Activity
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| Creator |
M Abdullahil Baki; Institute of Biological Sciences, University of Rajshahi, Rajshahi-6205
Golam Sadik; Phytochemistry Research Laboratories, Department of Pharmacy, University of Rajshahi, Rajshahi-6205 KAM Shahadat Hossain Mondal; Institute of Biological Sciences, University of Rajshahi, Rajshahi-6205 M Ashilk Mosaddik; Phytochemistry Research Laboratories, Department of Pharmacy, University of Rajshahi, Rajshahi-6205 M Mukhlesur Rahman; Phytochemistry Research Laboratories, Department of Pharmacy, University of Rajshahi, Rajshahi-6205 |
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| Subject |
Pharmacy
Derris indica; Leguminosae; Methylkarranjic acid; Pongamol; Antibacterial activity |
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| Description |
Two phenolic compounds, methylkarranjic (1) acid and pongamol (2), were isolated from the petroleum ether soluble fraction of an ethanolic extract of Derris indica seeds. The structures of these compounds were confirmed by LC-MS and a series of 1D and 2D NMR data. The solvent solvent partionates of the ethanolic extract and compounds (1 and 2) exhibited moderate antibacterial activity against several test organisms. The minimum inhibitory concentrations (MICs) of 1 and 2 were found to be in the range of 32-128 μg/ml against Bacillus megatorium, Streptococcus β-haemolyticus, Shigella dysenteriae and E. coli.
Key words: Derris indica; Leguminosae; Methylkarranjic acid; Pongamol; Antibacterial activity
Dhaka Univ. J. Pharm. Sci. 6(1): 9-13, 2007 (June)
The full text is of this article is available at the Dhaka Univ. J. Pharm. Sci. website
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| Publisher |
Dhaka University
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| Date |
2007-08-09
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| Type |
—
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| Format |
application/pdf
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| Identifier |
http://www.banglajol.info/index.php/JPharma/article/view/337
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| Source |
Dhaka University Journal of Pharmaceutical Sciences; Vol 6, No 1 (2007); 9-13
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| Language |
en
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| Coverage |
Bangladesh
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