Isolation of Bioactive Secondary Metabolites from the Endophytic Fungus of Ocimum basilicum
Bangladesh Journals Online
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| Title |
Isolation of Bioactive Secondary Metabolites from the Endophytic Fungus of Ocimum basilicum
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| Creator |
Md. Aminul Haque; Department of Chemistry, University of Dhaka, Dhaka-1000
M Shawkat Hossain; Department of Chemistry, University of Dhaka, Dhaka-1000 MZ Rahman; Department of Microbiology, University of Dhaka, Dhaka-1000 M Rezaur Rahman; Department of Chemistry, University of Dhaka, Dhaka-1000 Md. Sohrab Hossain; Department of Chemistry, University of Dhaka, Dhaka-1000 M Mosihuzzaman; Department of Chemistry, University of Dhaka, Dhaka-1000 Nilufar Nahar; Department of Chemistry, University of Dhaka, Dhaka-1000 SI Khan; Department of Microbiology, University of Dhaka, Dhaka-1000 |
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| Subject |
Pharmacy
Ocimum basilicum; Secondary Metabolites; Endophytic fungi; Ergosterol; Cerevesterol |
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| Description |
Twenty three endophytic fungi from leaf, stem and root of 0cimum basilicum (Tulshi) were isolated and purified. One of the fungi (2L-5) isolated from the leaves was fermented in a large scale and extracted with ethyl acetate. The fungal extract was found to be active against two bacteria, Bacillus cereus and Staphylococcus aureus. From the ethyl acetate extract two steroids, ergosterol and cerevisterol were isolated. Structures of the compounds were elucidated by high-resolution 1- and 2-D NMR spectroscopy.
Key words: Ocimum basilicum, Secondary Metabolites, Endophytic fungi, Ergosterol, Cerevesterol
Dhaka Univ. J. Pharm. Sci. Vol.4(2) 2005
The full text is of this article is available at the Dhaka Univ. J. Pharm. Sci. website
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| Publisher |
Dhaka University
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| Date |
2007-06-18
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| Type |
—
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| Identifier |
http://www.banglajol.info/index.php/JPharma/article/view/215
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| Source |
Dhaka University Journal of Pharmaceutical Sciences; Vol 4, No 2 (2005)
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| Language |
en
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